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KMID : 1143420210140160922
Public Health Weekly Report
2021 Volume.14 No. 16 p.922 ~ p.929
COVID-19 Variant Surveillance in the Republic of Korea
Kim Il-Hwan

Park Ae-Kyung
Kim Jeong-Min
Kim Heui-Man
Lee Nam-Joo
Woo Sang-Hee
Lee Chae-Young
Lee Jae-Hee
Rhee Jee-Eun
Kim Eun-Jin
Abstract
Coronavirus disease (COVID-19) variants originating from the United Kingdom (UK), South Africa, and Brazil have recently
spread throughout the world, and these variants are known to be different from non-variants in their transmissibility and
immune effect. Accordingly, the World Health Organization has recommended public health measures for variants and
proposed working definitions of variants of concern (VOCs) and variants of interest (VOIs).
The Korea Disease Control and Prevention Agency (KDCA) has been regularly monitoring the genotype and mutations of
SARS-CoV-2, the virus that causes COVID-19, through whole-genome sequencing analysis from the initial outbreak of COVID-19 in the Republic of Korea on January 20, 2020 to the present. As a result, 162 cases of VOCs originating from the UK (138), South Africa (18), and Brazil (6) and 61 cases of VOIs originating from California, USA (55), New York, USA (3) and the UK/ Nigeria (3) were identified early, and the genomic information of the variants confirmed through surveillance were shared with the GISAID database for international collaboration. To cope with the continuing spread of COVID-19 variants, the KDCA is continuing to strengthen its surveillance system by expanding its analytical capacity. This report was intended to help establish countermeasures to prevent the spread of variants by providing information on the characteristics of variants occurring in the Republic of Korea and internationally, and by reporting the results of domestic surveillance.
KEYWORD
Coronavirus disease (COVID-19), Virus variant, Whole-genome sequencing analysis
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